The worst ending in Cyberpunk 2077 - is definitely suicide. You can choose this ending if you have a save at the point of no return. Only then you can replay and choose a more happy ending. Let's go!

It's simple here: When Misty takes you to the balcony, you will start a conversation with Johnny. During the conversation, the option of suicide will become available to you. Click on the phrase "We can do it right now," and then answer "Yes, we will do it". After that, you will get rid of all the omega-blockers and shoot yourself. Everyone will be sorry for what happened.

In the end, you die, and you are left without achievements. But fortunately, this outcome is very easy to avoid! To find out how to get the best or secret ending read here.